Analysis of a Novel Translocation, T(9;17)(Q31;Q24), in Rosette-Forming Glioneuronal Tumors
نویسندگان
چکیده
منابع مشابه
Rosette-forming Glioneuronal Tumors in the Posterior Third Ventricle.
tumor found almost exclusively within the fourth ventricle. These grade I tumors were first included in the World Health Organization (WHO) Classification for the central nervous system in 20071. Since then, approximately 49 cases have been published1,2. There are no reported cases of RGNT within the third ventricle, although this tumor has also been described in the pineal region, the tectum a...
متن کاملFGFR1 mutations in Rosette-forming glioneuronal tumors of the fourth ventricle.
Rosette-forming glioneuronal tumors (RGNTs) are rare glioneuronal tumors of the fourth ventricle region that preferentially affect young adults. Despite their histologic similarity with pilocytic astrocytomas (PAs), RGNTs do not harbor KIAA1549-BRAF fusions or BRAF mutations, which represent the most common genetic alteration in PAs. Recently, mutations affecting the hotspot codons Asn546 and L...
متن کاملCase Report Gene alteration of rosette-forming glioneuronal tumor in a supurasellar lesion
Background: Rosette-forming glioneuronal tumor (RGNT) in suprasellar lesions is exceedingly rare, and its clinicopathological features are distinctive. Case report: A 55-year-old woman was admitted with headache and visual field disturbance. Magnetic resonance imaging (MRI) revealed a mass lesion in a suprasellar lesion accompanied by obstructive hydrocephalus. Following surgery, pathological e...
متن کاملRosette-forming glioneuronal tumour of the 4th ventricle in a NF1 patient.
of the 4th ventricle in a 41 year-old man with neurofibromatosis type 1 (NF1). This patient had a family history of NF1 and presented with café-au-lait spots and multiple neurofibromata. At the age of 16 years (1983), he presented with severe headache and the head computed tomogram (CT) scan showed a 4th ventricular mass. The mass was partially resected and the histology was initially reported ...
متن کاملMolecular Profiling of a Rare Rosette-Forming Glioneuronal Tumor Arising in the Spinal Cord
Rosette-forming glioneuronal tumor (RGNT) of the IV ventricle is a rare and recently recognized brain tumor entity. It is histologically composed by two distinct features: a glial component, resembling pilocytic astrocytoma, and a component forming neurocytic rosettes and/or perivascular rosettes. Herein, we describe a 33-year-old man with RGNT arising in the spinal cord. Following an immunohis...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2014
ISSN: 0923-7534
DOI: 10.1093/annonc/mdu359.18